Discover active funding sources for Missouri organizations making a difference in their communities.

If you’re an individual, an organization, or a collective looking to make a meaningful impact in Missouri, several community grant opportunities are available to help fund projects that address critical needs, foster creativity, and drive change. From supporting local artists to promoting entrepreneurial growth, here’s a detailed look at some key grants you can apply for in 2025.
1. 2025 Futures Grant Fund
The Futures Grant Fund is an excellent opportunity for visual artists and collectives within the St. Louis region to bring innovative and collaborative art projects to life. This grant is specifically focused on fostering sustainable art practices that engage local communities while keeping accessibility and inclusivity at the forefront.
Key Details:
Funding Amount: $2,500–$8,000
Eligible Projects:
Artist-driven initiatives in the visual arts
Public art installations, murals, or outdoor sculptures
Innovative collaborations between artists and community members
Educational projects involving visual arts with public-facing programs
Application Deadline: May 5, 2025
If you’re a visual artist with a strong desire to make a difference in the St. Louis area, this grant is an outstanding opportunity to combine sustainability with creativity.
2. Until She’s Free Grant Fund 2025
This grant, created by the Circle for Justice Innovations, provides support to organizations led by women, girls, trans, and gender-expansive individuals working to address issues related to incarceration, state-sanctioned violence, and systemic inequality. It’s designed for those advocating for foundational changes and justice for the most marginalized groups.
Focus Areas:
Ending the abuse-to-prison pipeline
Clemency campaigns for women in prison
Restoring rights for justice-involved women and girls
Family reunification and fighting unjust incarceration-based separation
Eligibility:
Organizations must be led by formerly incarcerated or affected individuals
Budgets must not exceed $750,000
The organization must have an active system-change strategy
Application Deadline:
Submission Date: May 12, 2025
This is an opportunity to challenge systemic oppression and push for justice while amplifying marginalized voices.
3. 2025 Physical Infrastructure Grant Program
This grant is focused on enabling entrepreneurship by providing financial support for physical infrastructure, such as coworking spaces, biotech labs, or other facilities needed for innovation. Any nonprofit organization in Missouri managing such infrastructure is invited to apply.
Key Details:
Grant Amount: Up to $200,000 or 25% of annual operating costs
Eligible Applicants:
Public or private nonprofit Missouri research institutions
Nonprofit entrepreneurial support organizations
Grant Duration:
Options for one-, two-, or three-year operational plans
Application Deadline: May 14, 2025
This grant allows entrepreneurs across Missouri to gain access to spaces and tools they otherwise couldn’t afford, further bolstering the state’s innovative economy.
4. 2025 Heal the Healers Grant Fund
Offered by the Joyful Heart Foundation, the Heal the Healers Grant provides support to professionals working with survivors of domestic violence, sexual assault, and child abuse. This grant focuses on addressing vicarious trauma and ensuring that “healers” themselves are cared for.
Highlights:
Funding Amount: Up to $5,000
Eligible Expenses:
Training in self-care techniques such as yoga or somatic therapy
Equipment like daylight lamps or ergonomic furniture
Staff initiatives to foster well-being, such as team-building activities
Extra Perks:
Access to a peer-learning community
Virtual professional development sessions
Application Deadline: May 14, 2025
This grant is ideal for nonprofits and government agencies that provide critical support services and want to sustain the well-being of their dedicated teams.
5. Drug-Free Communities (DFC) Grant
This federally funded program provides resources to prevent youth substance abuse through grassroots coalitions. Community-based coalitions can receive up to 10 years of funding to engage youth in positive activities and tackle substance abuse within their communities.
Objectives:
Focus substances include alcohol, marijuana, prescription drugs, tobacco, heroin, and methamphetamine
Encourage initiatives like youth mentoring and awareness campaigns
Eligibility:
Nonprofits or community-based coalitions
Partnerships with organizations like schools, local governments, or healthcare professionals
If your coalition is tackling substance abuse in Missouri, this program offers long-term support needed to sustain community-based preventative strategies.
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Take the Opportunity to Make an Impact
These grants represent an incredible opportunity to utilize funding for meaningful and impactful work that can change the lives of individuals and communities across Missouri. Whether you’re an artist, entrepreneur, healer, or advocate for justice, these programs align with your passion and goals.
Start your application process today, and don’t miss out on the chance to bring a vision to life. Many of these deadlines are approaching quickly, so be sure to take the next step and read through the application requirements. Empower your community with the funding it needs to thrive!
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